Its functions include pivotal roles in the proteasome-mediated protein degradation pathway, coordination of the endoplasmic reticulum stress response, and, more intriguingly, recent findings have associated DNAJB1 with the progression of neoplastic disorders, emphasizing its significance as a versatile modulator of cellular homeostasis and disease pathogenesis (57–59). The gene discussed is DNAJB1; the disease is neoplastic disease or syndrome.