In terms of immune cell infiltration and function, the low-risk group exhibited significantly higher levels of various immune cells, including aDCs, B cells, CD8+ T cells, among others (Figure 5F).Correspondingly, this group also showed heightened activity in several immune functions like APC co-inhibition, CCR, and type II interferon response (Figure 5G), suggesting a more active and potentially effective immune surveillance against tumor cells. The gene discussed is CD8A; the disease is neoplasm.