HIF1A and gastric cancer: Focusing on the frontiers and scientific issues, this study is dedicated to elucidating the molecular mechanism of HIF1α overexpression in gastric cancer cells under normoxic conditions, expanding the new understanding of m6A modification in the regulation of glucose metabolism and radiotherapy resistance in gastric cancer, and revealing the effect of a new class of m6A reading proteins on the sensitivity of gastric cancer to radiotherapy.