IL18R1 and infection: CHIKV infection led to the upregulation of multiple chemokines (CXCL5, CXCL3, and CXCL9), substantial upregulation of address in genes, IL1a, IL15, and IL18r in the blood (Figure 4(g,h)), and similarly in the GI tract (Figure 5(a,b)), which was primarily driven by infection rather than antibiotic treatment.