TARDBP and amyotrophic lateral sclerosis: Fatima and colleagues evaluated the distribution of phosphorylated TDP-43 inclusions in oligodendrocytes across the CNS of post-mortem ALS cases by immunohistochemistry (N = 34), and found abundant oligodendrocyte phosphorylated TDP-43 pathology in affected grey matter regions – but not in connecting deep white matter tracts [92].