This is further supported by recruitment of the cargo transport protein transportin-1 (also named Importin-β2, which mediates nuclear import of FET proteins) to FUS/EWS/TAF15-containing pathological inclusions in FTLD, but not FUS-containing inclusions in ALS [65, 137, 138]. Here, TNPO1 is linked to amyotrophic lateral sclerosis.