Quantitative analysis showed: GPR43-OE group displayed intermediate living number cells in both cortex (control: 47.50 ± 4.56; AD:21.75 ± 3.35; GPR43-OE: 32.75 ± 2.06; p < 0.05; Fig. 3B) and hippocampus (control: 71.25 ± 5.79; AD:33.00 ± 2.42; GPR43-OE:45.75 ± 4.50; p < 0.05; Fig. 3C) by H&E staining. Here, FFAR2 is linked to Alzheimer disease.