Although CDKN2 A expression was not markedly higher under IFNγ‐C than under acute IFNγ (IFNγ‐24 h) stimulation (Fig. 2B), the reduced cell density (Fig. 3A), lower cumulative population doubling (Fig. 3B), and downregulation of proliferation‐associated genes in late passage group (CCNA2, CCNB1, MKI67) in IFNγ‐C-treated cells (Fig. 2B), suggest that prolonged inflammatory stress impairs AD‐MSCs proliferation. This evidence concerns the gene IFNG and Alzheimer disease.