Noteworthy, mutations in BAG3, the obligatory partner of HSPB8, cause cardiomyopathy, besides neuropathy and myopathy [33–36], and mutations in other HSPBs (HSPB5, HSPB6, and HSPB7) also associate with cardiac pathology [37]. This evidence concerns the gene HSPB8 and cardiomyopathy.