As shown in Fig. 2D, the cell lines transfected with siRXRG migrated significantly less cells than the control cells after 24 h of seeding (P < 0.001) Overall, the concordant suppression of proliferation, clonogenicity, and migration following RXRG knockdown strongly supports its role as an oncogene in thyroid tumorigenesis. The gene discussed is RXRG; the disease is thyroid gland disorder.