NPPB and COVID-19: We evaluated these shifts prospectively using a 14-day rolling window across the following periods: (1) from March 1, 2015, to July 31, 2016, to overlap the decrease in D-dimer tests; (2) from September 1, 2017, to January 31, 2019, to overlap the decrease in BNP tests; and (3) from March 1, 2019, to June 30, 2020, to overlap the start of the COVID-19 pandemic (eFigure 4 in Supplement 1).