Although our prior studies did not reveal any significant differentiation of the RDEB wound-derived T cells toward Th17 ex vivo in the presence of Staphylococcus aureus antigens [15] observing IL-17 and IL-18 in RDEB established lesions point to bacteria-induced T cell differentiation toward Th17 cells at wounded sites. This evidence concerns the gene IL17A and recessive dystrophic epidermolysis bullosa.