Additionally, the association between dietary ω6/ω3 PUFA ratio and pediatric CD occurrence seemed to be significantly dependent on the CYP4F3 genotypes (rs1290617 and rs1290620) and FADS2 genotypes (rs11230815, rs17831757, rs968567, and rs174627).48 The gene discussed is CYP4F3; the disease is Cowden disease.