Published studies have uncovered that TNBC is enriched in ferroptosis-related gene signature and co-inhibition of BET and that proteasome induced ferroptosis in all major TNBC subtypes (BL1/2 and M/MSL), while targeting BET and CXCR2 induced tumor cell apoptosis in mesenchymal TNBC subtype (19). Here, DNER is linked to neoplasm.