SHBG and diabetes mellitus: However, significant negative correlations were found in the following subgroups (P<0.05): age (<65 years), Non-Hispanic White, education level (high school or below), marital status (married or cohabiting), PIR<3.50, smoking status (yes or no), alcohol consumption (yes or no), hypertension (yes or no), hyperlipidemia (absent), diabetes (absent), testosterone levels (≤4.02 or ≥5.78 ng ml-1), SHBG (≥28.2 nmol l-1), E2 (≤34.62 pg ml-1), and ADLG (≤5.64 or ≥8.33 ng ml-1).