CKM and squamous cell carcinoma: MYL3 not only acts as a slow muscle fibre, but also serves as a biomarker of poor prognosis in squamous cell carcinoma of the head and neck markers (Li et al., 2023).CKM is an M-type creatine kinase involved in catalysing the transfer of phosphate groups between ATP and phosphocreatine, which in turn affects energy metabolism in the heart (Bertero and Maack, 2018).