MYL3 not only acts as a slow muscle fibre, but also serves as a biomarker of poor prognosis in squamous cell carcinoma of the head and neck markers (Li et al., 2023).CKM is an M-type creatine kinase involved in catalysing the transfer of phosphate groups between ATP and phosphocreatine, which in turn affects energy metabolism in the heart (Bertero and Maack, 2018). This evidence concerns the gene MYL3 and squamous cell carcinoma.