CYP3A5 and hypertensive disorder: CYP3A5 activity score was nominally associated with lower DBP (β = −0.10 mmHg, 95% CI: −0.18 to −0.02, P = 0.01; Figure 3), but not with SBP (P = 0.57), MAP (P = 0.09; Figure 3), or HTN (P = 0.94; Figure 4).