RACGAP1 and cancer: Among these, RACGAP1, a member of the Rho GTPase-activating protein family, is primarily known for critical roles in cytokinesis, cell migration, and invasion, through its regulation of cytoskeletal dynamics and signaling pathways.13,14 While RACGAP1 has been extensively studied in cancer biology—where its overexpression is associated with poor prognosis across various malignancies—its role in immune responses remains poorly understood.