APOA1 and atherosclerosis: It is speculated that Hp infection may lead to the increase of ApoB/ApoA1 by causing the occurrence and development of inflammation in the host, and the increase of ApoB/ApoA1 is involved in the interaction between Hp and host cells, and mediates the further progress of inflammation, ultimately leading to atherosclerosis and increased risk of cardiovascular and cerebrovascular diseases.