TMPRSS11D and eosinophilic gastrointestinal disease: Increased basal serum trptase levels were seen in 16% (15/92) subjects with EGID but <1% (1/143) of patients with atopic dermatitis with eosinophilia. Of the 15 subjects with EGID, 4 patients were found to have HαT as cause of elevated basal tryptase.