Among the 17 SNPs included in our analysis model, CDKAL rs7756992, SLC30A8 rs3802177, CDKN2B rs10811661, and KCNQ1 rs2237895 showed strong associations with T2D across multiple models, consistent with previous findings [15, 32]. The gene discussed is KCNQ1; the disease is type 2 diabetes mellitus.