SLC7A5 and nervous system disorder: LAT1 is overexpressed in many types of tumors and mediates the transfer of drugs and hormones across the blood-brain barrier.41 Over the years, interest in LAT1 has increased because this transporter is involved in important human diseases such as neurological disorders and cancer.42 Therefore, LAT1 has become an important pharmacological target together with other nutrient membrane transporters.43