RHO and retinitis pigmentosa: In mouse models of retinitis pigmentosa (RP) with photoreceptor degeneration, including for the well-characterized misfolding P23H-Rho mutation (Kaushal and Khorana, 1994; Saliba et al., 2002), Rho is mislocalized not only to the rod IS and cell body but also to the OPL (Barhoum et al., 2008; Hagstrom et al., 1999).