CD36 and rheumatoid arthritis: First of all, even though this work demonstrated that CD36 was highly expressed in RA-FLS, and the data in GSE93272 suggested that it was up-regulated in the peripheral blood samples of RA patients, its diagnostic value should be further validated with a larger cohort with more patients from different medical centers, especially the AUC in the present dataset was less than 0.7, which was not suitable for clinical application.