TTN and esophageal squamous cell carcinoma: Furthermore, lncRNA TTN-AS1, identified as an oncogene in ESCC, promotes the expression of the transcription factor Snail1 through competitive binding with miR-133b, thereby facilitating the epithelial-mesenchymal transition (EMT) process; additionally, it can enhance ESCC invasion by sponging miR-133b to induce the expression of FSCN1 [10].