Additionally, rs215539 (r = 0.501, p = 0.004) in CPXM1, which is associated with tumor progression and immune cell infiltration [23], and rs1332664 (r = 0.484, p = 0.005) in CFHR5, a gene related to complement regulation [24], were also significantly associated with general fatigue. Here, CPXM1 is linked to neoplasm.