Furthermore, Liu et al. demonstrated that epigallocatechin gallate, a polyphenolic compound derived from tea leaves, specifically attenuates cGAS-dependent IFN production in AGS patient cells and AGS mouse model by disrupting the interaction between G3BP1 and cGAS (Liu et al. 2019). The gene discussed is IFNA1; the disease is Aicardi-Goutieres syndrome.