Also, the Bt-toxin resistant (bre) mutants bre-2(ye31) and bre-3(ye26), which are defective in the biosynthesis of the Cry5B glycosphingolipid receptor47, are susceptible to Bt247 infection and still protected by MYb115 (Fig. S19B and Supplementary Data 14). The gene discussed is ASH2L; the disease is infection.