IAPP and steatosis: Rodent non-alcoholic steatohepatitis (NASH) models can be developed by overnutrition using modified diets (e.g., Western diet, Gubra-Amylin NASH diet, et cetera); the continuum between steatosis and the lipotoxic effects causing heptatocellular damage and lobular inflammation vary depending on the genetic background of the rodent and the specific components of the NASH-inducing diets [47].