INS and Neurodevelopmental delay: This means that thedepolarization (ρ) spectrum can provide additional structuralinformation about a molecule or mixture including the molecular orientationof functional groups, as demonstrated for insulin fibrils. Therefore, we hypothesized that samples fromeach of the different NDD tissues could have a distinct depolarizationprofile due in part to variations in the tau protein fibrils withineach disease. Raman (ρ) fingerprintsusing 785 nm excitation are shown in Figure S1.