IL1RAP and necrotizing enterocolitis: However, several other inflammation-associated genes, including IL1R2, IL1RAP, IL1RA, IL6ST, IL6RA, TNFAIP3, TLR6, TLR10, TGFB1I1, TNFRSF10 A, TNFRSF10D, and TNFRSF13 C, were significantly upregulated in NEC patients (Fig. 5).