Although the ROC analysis of GABRP showed a low diagnostic efficacy (AUC values of 0.584 and 0.587), its expression was significantly correlated with the overall survival of patients (HR = 1.8, p = 0.008), and in vitro experiments confirmed that GABRP knockout could inhibit tumor cell invasion (p < 0.001). This evidence concerns the gene GABRP and neoplasm.