Likewise, JBNU-22-N01 infection showed significantly increased levels of lung IFN-α, IFN-γ, IL-1β, and IL-12p40 at 7 dpi, indicating a faster disease progression and host response than PJ73 or VR2332 (Fig. 8B), which is likely to be correlated with faster virus replication (Fig. 11). Here, IFNA1 is linked to infection.