ABCC3 and type 2 diabetes mellitus: In our research, the levels of Cyp7a1 and Cyp7b1 in the liver were significantly lower than those in the T2DM group, and the level of Abcc3 was significantly greater in the FCJ/RCJ intervention groups than in the T2DM group (p < 0.001), which resulted in the removal of excessive bile acids to protect the liver and maintain bile acid synthesis balance through enterohepatic circulation.