Malnutrition risk, was assessed by preoperative validated Malnutrition Universal Screening Tool (MUST) score ≥2, lymphocyte count <900 n/mm3, albumin value <3.5 g/dL or a combination of the previous two parameters, the Prognostic Nutritional Index (PNI) < 45; inflammation was evaluated using preoperative Neutrophil-to-Lymphocyte Ratio (NLR) > 5, Platelet-to-Lymphocyte Ratio (PLR) > 150 and Lymphocyte-to-Monocyte Ratio (LMR) < 5. The gene discussed is ALB; the disease is nutritional deficiency disease.