This includes blocking “do not eat me” signals like CD47-SIRPα or CD24-Siglec-10 to enhance phagocytosis by macrophages, inhibiting monocyte recruitment or differentiation via pathways like CSF-1/CSF-1R, or attempting to repolarize M2-like TAMs towards an anti-tumor M1-like state. Here, SIRPA is linked to neoplasm.