TPMT and hematopoietic and lymphoid system neoplasm: Additionally, 49 (30.4%), 47 (29.2%), 67 (41.6%), and 55 (34.2%) respondents expressed beliefs that blood cancer is hereditary, TPMT variants alone do not explain all thiopurine toxicity, severe ADRs related to TPMT genetic variants have been identified, and there are ethnic differences in the TPMT gene, respectively.