Using the standard cutoff values recommended by the commercial test kits manufacturers for ECLIA Elecsys CA-125, CA 19-9, CYFRA 21–1 and SCC, ELISAs CA15-3-IFA-BEST, CEA-IFA-BEST, NSE-IFA-BEST and CLIA-CA-62 were calculated their diagnostic parameters for all NSCLC stages (I-III). This evidence concerns the gene ENO2 and non-small cell lung carcinoma.