In this article we evaluated the diagnostic characteristics of the CLIA-CA-62 set of reagents for the detection of early (I-II) and advanced stages of lung cancer in patients with pathological changes on the CT scan compared to other tumor markers (CEA, CA-125, CA15-3, SCC, CYFRA 21-1, NSE and CA 9-19) on a cohort of 304 patients. The gene discussed is ENO2; the disease is neoplasm.