VEGFA and neoplasm: Ginsenoside is mainly extracted from Araliaceae ginseng plants, with anti-tumor and immune-enhancing functions, has been found to inhibit excessive HIF-1α and VEGF expression and down-regulate proteins such as Heat Shock Factor protein 1, Glucose Transporter 1, and Glucose Transporter 4, inhibiting early angiogenesis, improving microvessel morphology, and alleviating hypoxia tolerance in gastric mucosa, effectively shortening PLGC range (18, 19).