Analyses across the two scRNA datasets showed that sub-clusters 2 and 3 in the 1st dataset and sub-clusters 1 and 2 in the 2nd dataset had high expression of CD14 and IL1B, and larger scores for the INFLAM (inflammatory cytokine-enriched) and TIM (tumor infiltrating monocytes) gene signatures (these two macrophage sub-clusters are therefore named as “TIM” sub-clusters from here). Here, CD14 is linked to neoplasm.