,25,26 In an additional study of TB patient sera, while TB-specific phagocytic function was similar across patients with TBI or TB disease, TBI patients possessed PPD-specific IgG levels with higher affinity for FcγRIIIa which was associated with enhanced antimicrobial functions, such as NK cell-mediated antibody-dependent cellular cytotoxicity and degranulation.11 This evidence concerns the gene FCGR3A and tuberculosis.