ADIPOQ and periodontal disorder: Toxins such as leptin, tumour necrosis factor-α, adiponectin, angiotensinogen, and C-reactive peptide are estimated to induce inflammation in periodontal tissues.12 Moreover, the obese subjects tend to consume food with high sugar, and those with increased weight tend to be less concerned with maintaining oral health, which increases the risk for the development of periodontal disease.