KDM4C and breast carcinoma: To investigate mechanisms underlying KDM4C-loss-mediated growth inhibition, we first performed RNA sequencing (RNA-seq) in four Dox-inducible shKDM4C-expressing basal breast cancer cell lines, including KDM4C-amplified (HCC1954 and SUM149) and KDM4C-non-amplified (HCC1806 and HDQP1) cells.