The intrinsic source of native soluble LIGHT and LTα1β2 (produced by neutrophils and activated T cells and NK cells) along with the tumor secreting recombinant Ig.Foldon-LIGHT co-stimulate NK and T cells through HVEM and license DC for antigen presentation to promote anti-tumor T cell responses in the tumor draining lymph nodes. Here, TNFSF14 is linked to neoplasm.