IL17RE and infection: Further, we also identify IL17D, IL17RE and IL17RC, gene which is part of interleukin-17 group, this gene act by regulating the cytokine production and influence the recruitment of innate immune cells to infection areas60.For instance In humans, the IL17RE gene have been seen to work in conjunction with IL17RA to drive IL-17 C-mediated mucosal and TH17 immune responses61, These interactions are important as they play a role of enhanced immunity62.