GPT and infection: Finally, we detected the liver damage indicators AST and ALT, infection with C. sinensis caused increases of AST and ALT in mice serum, while treatment with Fer-1 significantly decreased the AST content in mice serum at 35 d.p.i (50.1%) (Fig 6E), Fer-1 treatment also significantly decreased the ALT contents in mice serum at 7 d.p.i, 18 d.p.i, 35 d.p.i (85.3%, 96.0%, 88.9%) (Fig 6F).