Specifically, low-income individuals often require more insulin due to poor diabetes management and are at high risk of neglect due to hypoglycemia unawareness, both stemming from a lack of education on advanced diabetes care.9 Additionally, they have higher rates of major comorbidities, including CKD, a significant risk factor for hypoglycemia.18 Low-income individuals also face nutritional imbalances, leading to both obesity and a higher risk of being underweight, further increasing their risk of severe hypoglycemia. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.