CXCL1, a member of the chemokine family, is related to tumor cell invasion (stage T2-T4), lymph node metastasis, venous invasion, peritoneal cytological manifestations, peritoneal metastasis, and CXCR2 expression in stromal cells in the GC microenvironment, showing its role in tumor progression and prognosis [47] [48]. The gene discussed is CXCR2; the disease is neoplasm.