The results indicated that low CADPS expression was an independent prognostic predictor of OS for the entire pediatric ALL cohort (HR ═ 2.329, 95% CI: 1.493–3.632, P < 0.001) and for FG-negative ALL patients (HR ═ 2.350, 95% CI: 1.406–3.930, P< 0.001) (Tables 3–4).Using clinical variables from 129 FG-negative ALL patients, we applied the Cox method to generate a nomogram plot and calculate risk scores (Figure 4A). Here, CADPS is linked to acute lymphoblastic leukemia.