An inquiry into the Cancer Genome Atlas-Pancreatic Adenocarcinoma (TCGA-PAAD) cohort (20) for mutations and Genomic Identification of Significant Targets in Cancer (GISTIC) putative copy number alterations (CNAs) (23) revealed frequent heterozygous loss of PBRM1. The gene discussed is PBRM1; the disease is pancreatic adenocarcinoma.