Shared terms between datasets for biological pathways known to be highly relevant to ALS/FTD included “establishment of protein localization” (SH-SY5Y and i3Neurons) and “cytoskeleton organization” (SH-SY5Y and SK-N-BE[2]), and shared terms for GO molecular functions were “kinase activity,” “protein kinase binding,” and “cytoskeletal protein binding” (SH-SY5Y and SK-N-BE[2]). Here, WEE1 is linked to amyotrophic lateral sclerosis.